Translational Control: Selective Upregulation of ECM Components Drives Tumour Growth
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چکیده
منابع مشابه
Translational Control: Selective Upregulation of ECM Components Drives Tumour Growth
A new mechanistic link has been identified between the expression of initiator methionine tRNA and cancer progression, whereby elevated levels of this tRNA specifically drive synthesis of secretome components, resulting in a type II collagen-rich matrix that promotes tumour progression.
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1Department of Enterprise Engineering, Intrauniversitary Consortium for Material Science and Technology (INSTM), Research Unit “Tor Vergata”, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome, Italy 2INAIL-DIPIA, Via Alessandria 220E, 00198 Rome, Italy 3Surgery Unit, Institute of Child Health and Great Ormond Street Hospital, University College London, 30 Guilford Street, Lond...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2016
ISSN: 0960-9822
DOI: 10.1016/j.cub.2016.01.053